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Statistical mechanics of warm and cold unfolding in proteins

arXiv:cond-mat/9711291 · doi:10.1007/s100510050537

Abstract

We present a statistical mechanics treatment of the stability of globular proteins which takes explicitly into account the coupling between the protein and water degrees of freedom. This allows us to describe both the cold and the warm unfolding, thus qualitatively reproducing the known thermodynamics of proteins.

5 pages, REVTex, 4 Postscript figures