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Replica-exchange multicanonical algorithm and multicanonical replica-exchange method for simulating systems with rough energy landscape

arXiv:cond-mat/0009119 · doi:10.1016/S0009-2614(00)00999-4

Abstract

We propose two efficient algorithms for configurational sampling of systems with rough energy landscape. The first one is a new method for the determination of the multicanonical weight factor. In this method a short replica-exchange simulation is performed and the multicanonical weight factor is obtained by the multiple-histogram reweighting techniques. The second one is a further extension of the first in which a replica-exchange multicanonical simulation is performed with a small number of replicas. These new algorithms are particularly useful for studying the protein folding problem.

9 pages, (ReVTeX), 7 figures. Chem. Phys. Lett. (2000), in press