Publications (32)
Spectral solutions to stochastic models of gene expression with bursts and regulation
Andrew Mugler, Aleksandra M. Walczak, Chris H. Wiggins
Limits to the precision of gradient sensing with spatial communication and temporal integration
Andrew Mugler, Andre Levchenko, Ilya Nemenman
Universality of biochemical feedback and its application to immune cells
Amir Erez, Tommy A. Byrd, Robert M. Vogel +2
Serially-regulated biological networks fully realize a constrained set of functions
Andrew Mugler, Etay Ziv, Ilya Nemenman +1
Noise expands the response range of the Bacillus subtilis competence circuit
Andrew Mugler, Mark Kittisopikul, Luke Hayden +4
Communication shapes sensory response in multicellular networks
Garrett D Potter, Tommy A Byrd, Andrew Mugler +1
Emergent versus Individual-based Multicellular Chemotaxis
Julien Varennes, Sean Fancher, Bumsoo Han +1
Telling time with an intrinsically noisy clock
Andrew Mugler, Aleksandra M. Walczak, Chris H. Wiggins
Diffusion vs. direct transport in the precision of morphogen readout
Sean Fancher, Andrew Mugler
Statistical properties of multistep enzyme-mediated reactions
Wiet H. de Ronde, Bryan C. Daniels, Andrew Mugler +2
Optimal Prediction by Cellular Signaling Networks
Nils B. Becker, Andrew Mugler, Pieter Rein ten Wolde
Analytic methods for modeling stochastic regulatory networks
Aleksandra M. Walczak, Andrew Mugler, Chris H. WIggins
Stochastic modeling of gene expression, protein modification, and polymerization
Andrew Mugler, Sean Fancher
Network motifs come in sets: correlations in the randomization process
Reid Ginoza, Andrew Mugler
The macroscopic effects of microscopic heterogeneity
Andrew Mugler, Pieter Rein ten Wolde
Physical constraints on accuracy and persistence during breast cancer cell chemotaxis
Julien Varennes, Hye-ran Moon, Soutick Saha +2
Prediction and Dissipation in Biochemical Sensing
Nils B. Becker, Andrew Mugler, Pieter Rein ten Wolde
The importance of crowding in signaling, genetic, and metabolic networks
Pieter Rein ten Wolde, Andrew Mugler
A statistical method for revealing form-function relations in biological networks
Andrew Mugler, Boris Grinshpun, Riley Franks +1
Sense and sensitivity: physical limits to multicellular sensing, migration and drug response
Julien Varennes, Andrew Mugler
Dynamic sampling and information encoding in biochemical networks
Garrett D. Potter, Tommy A. Byrd, Andrew Mugler +1
Spatial partitioning improves the reliability of biochemical signaling
Andrew Mugler, Filipe Tostevin, Pieter Rein ten Wolde
A stochastic spectral analysis of transcriptional regulatory cascades
Aleksandra M. Walczak, Andrew Mugler, Chris H. Wiggins
Cell-cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis
David Ellison, Andrew Mugler, Matthew Brennan +9
Collective chemotaxis through noisy multicellular gradient sensing
Julien Varennes, Bumsoo Han, Andrew Mugler
Protein logic: a statistical mechanical study of signal integration at the single-molecule level
Wiet de Ronde, Pieter Rein ten Wolde, Andrew Mugler
Membrane clustering and the role of rebinding in biochemical signaling
Andrew Mugler, Aimee Gotway Bailey, Koichi Takahashi +1
Temporal precision of regulated gene expression
Shivam Gupta, Julien Varennes, Hendrik C. Korswagen +1
Quantifying evolvability in small biological networks
Andrew Mugler, Etay Ziv, Ilya Nemenman +1
Fundamental limits to collective concentration sensing in cell populations
Sean Fancher, Andrew Mugler
Growth of bacteria in 3-d colonies
Xinxian Shao, Andrew Mugler, Justin Kim +3
Role of spatial averaging in multicellular gradient sensing
Tyler Smith, Sean Fancher, Andre Levchenko +2